Mwazaro Beach generally offers safe swimming conditions during high tide when the water is deeper. Like much of the Kwale coast, the beach experiences significant tidal variations, so low tide may expose coral and rocks. Currents are typically mild, but always observe local conditions before entering the water. The beach's secluded nature means fewer lifeguards or safety personnel, so swimmers should be cautious and avoid swimming alone. Wearing reef shoes is advisable to protect against sharp coral and sea urchins in shallow areas.

The best weather at Mwazaro Beach occurs from late December through March and July through October, when rainfall is minimal and sunshine is abundant. These periods also see less humidity and calmer seas. For travelers seeking fewer crowds, visit during shoulder seasons (April-May or November) when light rains occur but the beach remains relatively empty. The long rainy season (April-June) brings heavier downpours but dramatically fewer visitors. Water temperatures remain warm year-round, ranging from 25-28°C, making swimming pleasant in any season.