Mismaloya Beach offers generally safe swimming in its protected cove, with calmer waters than open-coast beaches. The bay provides natural shelter, though waves can pick up during certain conditions. Lifeguards are not always present, so swimmers should exercise personal judgment. The rocky areas at the cove's edges require caution. Snorkeling is popular here due to clear waters and marine life, but watch for boat traffic. The beach has a sandy bottom in most areas with some rocks. Swimming is best during morning hours when water is calmest.

Mismaloya Beach enjoys best weather from November through April, with sunny days, comfortable temperatures in the 70s-80s°F, and minimal rainfall. This period offers ideal conditions for beach activities and water sports. December through March see the most visitors but also the most reliable weather. May through October brings warmer, more humid conditions with occasional afternoon rain, particularly September and October. Early mornings provide the most peaceful atmosphere and best light for photography. The dry season ensures clear waters perfect for snorkeling and swimming.

Mismaloya Beach is located about 12 kilometers south of downtown Puerto Vallarta, easily accessible by multiple transportation options. Local buses marked 'Mismaloya' or 'Boca de Tomatlán' depart regularly from Puerto Vallarta and are the most economical choice. Taxis and ride-sharing services offer direct transportation, taking approximately 20-30 minutes depending on traffic. Many tour operators include Mismaloya in coastal excursions. If renting a car, follow Highway 200 south and watch for signage. The beach has parking available, though space can be limited during peak times.

Mismaloya Beach features several beachfront restaurants serving fresh seafood, ceviche, and Mexican favorites, many offering palapa seating with ocean views. Beach clubs provide chair and umbrella rentals, typically with food and beverage service. The area has a mix of accommodations, from budget-friendly hotels to the upscale La Jolla de Mismaloya resort overlooking the bay. Nearby small villages offer additional local eateries. Most restaurants accept both cash and cards, but bringing pesos is advisable. Vendors on the beach sell snacks, drinks, and souvenirs throughout the day.

Mismaloya Beach gained international fame as the filming location for the 1964 movie 'The Night of the Iguana,' starring Richard Burton and Ava Gardner. This production brought Hollywood glamour to the then-undiscovered area and helped establish Puerto Vallarta as a tourist destination. The beach maintains a charming village atmosphere despite development. Its scenic beauty, with the Mismaloya River meeting the ocean and jungle-covered mountains rising dramatically behind, creates a picturesque setting. Film history markers and the movie's legacy add cultural significance to the natural beauty.